Phosphatase PRL-3 is a direct regulatory target of TGFb in colon cancer metastasis

• Main Authors: Jiang, Y, Liu, X.-Q, Rajput, A, Geng, L, Ongchin, M, Zeng, Q, Taylor, G.S, Wang, J
• Other Authors: BIOCHEMISTRY
• Format: Article
• Published: 2020
• Subjects: cancer growth factor; cancer growth factor beta; prl 3 protein; protein tyrosine phosphatase; Smad protein; unclassified drug; animal cell; animal experiment; animal model; apoptosis; article; cancer survival; cell survival; colon cancer; controlled study; enzyme inhibition; gene overexpression; gene silencing; metastasis; mouse; nonhuman; priority journal; protein expression; signal transduction; Animals; Cell Line, Tumor; Chromatin Immunoprecipitation; Colonic Neoplasms; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Neoplastic; Mice; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-akt; Signal Transduction; Smad Proteins; Transforming Growth Factor beta
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/180976
• Institution: National University of Singapore

10.1158/0008-5472.CAN-10-1487