Long-term therapeutic silencing of miR-33 increases circulating triglyceride levels and hepatic lipid accumulation in mice

• Main Authors: Goedeke, L, Salerno, A, Ramírez, C.M, Guo, L, Allen, R.M, Yin, X, Langley, S.R, Esau, C, Wanschel, A, Fisher, E.A, Suárez, Y, Baldán, A, Mayr, M, Fernández-Hernando, C
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: antisense oligonucleotide; microRNA; Mirn33 microRNA, mouse; triacylglycerol; animal; blood; C57BL mouse; drug effects; fatty liver; gene silencing; genetics; lipid diet; lipid metabolism; liver; male; metabolism; Animals; Diet, High-Fat; Fatty Liver; Gene Silencing; Lipid Metabolism; Liver; Male; Mice, Inbred C57BL; MicroRNAs; Oligonucleotides, Antisense; Triglycerides
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/181747
• Institution: National University of Singapore

10.15252/emmm.201404046