Early oral stepdown antibiotic therapy versus continuing intravenous therapy for uncomplicated Gram-negative bacteraemia (the INVEST trial): study protocol for a multicentre, randomised controlled, open-label, phase III, non-inferiority trial

Early oral stepdown antibiotic therapy versus continuing intravenous therapy for uncomplicated Gram-negative bacteraemia (the INVEST trial): study protocol for a multicentre, randomised controlled, open-label, phase III, non-inferiority trial

10.1186/s13063-022-06495-3

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Bibliographic Details
Main Authors:	Lee, I Russel, Tong, Steven YC, Davis, Joshua S, Paterson, David L, Syed-Omar, Sharifah F, Peck, Kwong Ran, Chung, Doo Ryeon, Cooke, Graham S, Libau, Eshele Anak, Rahman, Siti-Nabilah BA, Gandhi, Mihir P, Shi, Luming, Zheng, Shuwei, Chaung, Jenna, Tan, Seow Yen, Kalimuddin, Shirin, Archuleta, Sophia, Lye, David C
Other Authors:	BIOCHEMISTRY
Format:	Article
Language:	English
Published:	BMC 2022
Subjects:	Science & Technology Life Sciences & Biomedicine Medicine, Research & Experimental Research & Experimental Medicine Gram-negative bacteraemia Antibiotics Early oral stepdown therapy Oral fluoroquinolones Oral trimethoprim-sulfamethoxazole Health economic evaluation Quality of life CIPROFLOXACIN INFECTION
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/230397
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Institution:	National University of Singapore
Language:	English

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Summary:	10.1186/s13063-022-06495-3