Early oral stepdown antibiotic therapy versus continuing intravenous therapy for uncomplicated Gram-negative bacteraemia (the INVEST trial): study protocol for a multicentre, randomised controlled, open-label, phase III, non-inferiority trial

• Main Authors: Lee, I Russel, Tong, Steven YC, Davis, Joshua S, Paterson, David L, Syed-Omar, Sharifah F, Peck, Kwong Ran, Chung, Doo Ryeon, Cooke, Graham S, Libau, Eshele Anak, Rahman, Siti-Nabilah BA, Gandhi, Mihir P, Shi, Luming, Zheng, Shuwei, Chaung, Jenna, Tan, Seow Yen, Kalimuddin, Shirin, Archuleta, Sophia, Lye, David C
• Other Authors: BIOCHEMISTRY
• Format: Article
• Language: English
• Published: BMC 2022
• Subjects: Science & Technology; Life Sciences & Biomedicine; Medicine, Research & Experimental; Research & Experimental Medicine; Gram-negative bacteraemia; Antibiotics; Early oral stepdown therapy; Oral fluoroquinolones; Oral trimethoprim-sulfamethoxazole; Health economic evaluation; Quality of life; CIPROFLOXACIN; INFECTION
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/230397
• Institution: National University of Singapore

10.1186/s13063-022-06495-3