Early oral stepdown antibiotic therapy versus continuing intravenous therapy for uncomplicated Gram-negative bacteraemia (the INVEST trial): study protocol for a multicentre, randomised controlled, open-label, phase III, non-inferiority trial

Early oral stepdown antibiotic therapy versus continuing intravenous therapy for uncomplicated Gram-negative bacteraemia (the INVEST trial): study protocol for a multicentre, randomised controlled, open-label, phase III, non-inferiority trial

10.1186/s13063-022-06495-3

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Bibliographic Details
Main Authors: Lee, I Russel, Tong, Steven YC, Davis, Joshua S, Paterson, David L, Syed-Omar, Sharifah F, Peck, Kwong Ran, Chung, Doo Ryeon, Cooke, Graham S, Libau, Eshele Anak, Rahman, Siti-Nabilah BA, Gandhi, Mihir P, Shi, Luming, Zheng, Shuwei, Chaung, Jenna, Tan, Seow Yen, Kalimuddin, Shirin, Archuleta, Sophia, Lye, David C
Other Authors: BIOCHEMISTRY
Format: Article
Language:English
Published: BMC 2022
Subjects:
Science & Technology
Life Sciences & Biomedicine
Medicine, Research & Experimental
Research & Experimental Medicine
Gram-negative bacteraemia
Antibiotics
Early oral stepdown therapy
Oral fluoroquinolones
Oral trimethoprim-sulfamethoxazole
Health economic evaluation
Quality of life
CIPROFLOXACIN
INFECTION
Online Access:https://scholarbank.nus.edu.sg/handle/10635/230397
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Institution: National University of Singapore
Language: English

Internet

https://scholarbank.nus.edu.sg/handle/10635/230397

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