Polygenic hazard scores in preclinical Alzheimer's disease

Polygenic hazard scores in preclinical Alzheimer's disease

Identifying asymptomatic older individuals at elevated risk for developing Alzheimer's disease (AD) is of clinical importance. Among 1,081 asymptomatic older adults, a recently validated polygenic hazard score (PHS) significantly predicted time to AD dementia and steeper longitudinal cognitive...

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書目詳細資料
Main Authors:	TAN, Chin Hong, HYMAN, Bradley T., TAN, Jacinth J. X., HESS, Christopher P., DILLON, William P., SCHELLENBERG, Gerard D., BESSER, Lilah M., KUKULL, Walter A., KAUPPI, Karolina, MCEVOY, Linda K., ANDREASSEN, Ole A., DALE, Anders M., FAN, Chun Chieh, DESIKAN, Rahul S.
格式:	text
語言:	English
出版:	Institutional Knowledge at Singapore Management University 2017
主題:	Polygenic risk Preclinical AD Diseases Psychology
在線閱讀:	https://ink.library.smu.edu.sg/soss_research/2744 https://ink.library.smu.edu.sg/context/soss_research/article/4001/viewcontent/Polygenic_hazard_scores_in_preclinical_Alzheimer_d__1_.pdf
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