Dihydroxypentamethoxyflavone down-regulates constitutive and inducible signal transducers and activators of transcription-3 through the induction of tyrosine phosphatase SHP-1
Because constitutive activation of signal transducers and activators of transcription-3 (STAT3) has been linked with cellular transformation, survival, proliferation, chemoresistance, and angiogenesis of various tumor cells, agents that can suppress STAT3 activation have potential as cancer therapeu...
Saved in:
Main Authors: | Phromnoi K., Prasad S., Gupta S., Kannappan R., Reuter S., Limtrakul P., Aggarwal B.B. |
---|---|
Format: | Article |
Language: | English |
Published: |
2014
|
Online Access: | http://www.scopus.com/inward/record.url?eid=2-s2.0-80054782411&partnerID=40&md5=025491561290998f19eed72532257715 http://cmuir.cmu.ac.th/handle/6653943832/3712 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Chiang Mai University |
Language: | English |
Similar Items
-
Dihydroxypentamethoxyflavone down-regulates constitutive and inducible signal transducers and activators of transcription-3 through the induction of tyrosine phosphatase SHP-1
by: Kanokkarn Phromnoi, et al.
Published: (2018) -
Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1
by: Rajendran, P., et al.
Published: (2014) -
Ginkgolic acid C 17:1, derived from Ginkgo biloba leaves, suppresses constitutive and inducible STAT3 activation through induction of PTEN and SHP-1 tyrosine phosphatase
by: Baek, S.H, et al.
Published: (2020) -
A novel pentamethoxyflavone down-regulates tumor cell survival and proliferative and angiogenic gene products through inhibition of IκB kinase activation and sensitizes tumor cells to apoptosis by cytokines and chemotherapeutic agents
by: Phromnoi K., et al.
Published: (2014) -
Identifikasi asam amino protein SHP yang berperan dalam terminasi signaling protein Signal Transducers and Avtivators of Transcription (STAT)
by: Anwar Maruf, Dr.,M.Kes.,drh, et al.
Published: (2012)