Dihydroxypentamethoxyflavone down-regulates constitutive and inducible signal transducers and activators of transcription-3 through the induction of tyrosine phosphatase SHP-1

Dihydroxypentamethoxyflavone down-regulates constitutive and inducible signal transducers and activators of transcription-3 through the induction of tyrosine phosphatase SHP-1

Because constitutive activation of signal transducers and activators of transcription-3 (STAT3) has been linked with cellular transformation, survival, proliferation, chemoresistance, and angiogenesis of various tumor cells, agents that can suppress STAT3 activation have potential as cancer therapeu...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Phromnoi K., Prasad S., Gupta S., Kannappan R., Reuter S., Limtrakul P., Aggarwal B.B.
التنسيق:	مقال
اللغة:	English
منشور في:	2014
الوصول للمادة أونلاين:	http://www.scopus.com/inward/record.url?eid=2-s2.0-80054782411&partnerID=40&md5=025491561290998f19eed72532257715 http://cmuir.cmu.ac.th/handle/6653943832/3712
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مواد مشابهة

Dihydroxypentamethoxyflavone down-regulates constitutive and inducible signal transducers and activators of transcription-3 through the induction of tyrosine phosphatase SHP-1
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