Synthesis of castanospermine
The diastereoselective synthesis of castanospermine is described in 11 synthetic steps from l-xylose. The borono-Mannich reaction between l-xylose, allylamine, and (E)-styrene boronic acid gives a tetrahydroxy amine with the desired configurations for C-6, C-7, C-8, and C-8a in the target molecule....
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2014
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| Online Access: | http://www.scopus.com/inward/record.url?eid=2-s2.0-39149142197&partnerID=40&md5=fc8cbeb31182e4e76906adca244818ad http://cmuir.cmu.ac.th/handle/6653943832/4485 |
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| Institution: | Chiang Mai University |
| Language: | English |