Design and synthesis of new potent N,N-bis(arylalkyl)piperazine derivatives as multidrug resistance (MDR) reversing agents
© 2018 Elsevier Masson SAS A series of 1,4-substituted arylalkyl piperazine derivatives were synthesized and studied with the aim to obtain potent P-gp-dependent multidrug-resistant (MDR) reversers. The new compounds were designed on the basis of the structures of our previous arylamine ester deriva...
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Main Authors: | Silvia Dei, Marcella Coronnello, Gianluca Bartolucci, Dina Manetti, Maria Novella Romanelli, Chatchanok Udomtanakunchai, Milena Salerno, Elisabetta Teodori |
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Format: | Journal |
Published: |
2018
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Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85041407631&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/48477 |
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Institution: | Chiang Mai University |
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