Maturation of flaviviruses starts from one or more icosahedrally independent nucleation centres
Flaviviruses assemble as fusion-incompetent immature particles and subsequently undergo conformational change leading to release of infectious virions. Flavivirus infections also produce combined mosaic particles. Here, using cryo-electron tomography, we report that mosaic particles of dengue virus...
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Main Authors: | Pavel Plevka, Anthony J. Battisti, Jiraphan Junjhon, Dennis C. Winkler, Heather A. Holdaway, Poonsook Keelapang, Nopporn Sittisombut, Richard J. Kuhn, Alasdair C. Steven, Michael G. Rossmann |
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Format: | Journal |
Published: |
2018
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Subjects: | |
Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79957981824&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/49715 |
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Institution: | Chiang Mai University |
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