Investigation of splicing changes and post-translational processing of LMNA in sporadic inclusion body myositis

Investigation of splicing changes and post-translational processing of LMNA in sporadic inclusion body myositis

Some features of sporadic inclusion body myositis (s-IBM) suggest that there is acceleration of the normal ageing process in muscle tissue. LMNA encodes the nuclear lamina proteins lamin A/C through alternative splicing, and aberrant splicing of exon 11 leads to the premature ageing disease, Hutchin...

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Bibliographic Details
Main Authors: Yue Bei Luo, Chalermchai Mitrpant, Russell Johnsen, Vicki Fabian, Merrilee Needham, Sue Fletcher, Steve D. Wilton, Frank L. Mastaglia
Other Authors: University of Western Australia
Format: Article
Published: 2018
Subjects:
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/32110
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/32110

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