Investigation of splicing changes and post-translational processing of LMNA in sporadic inclusion body myositis
Some features of sporadic inclusion body myositis (s-IBM) suggest that there is acceleration of the normal ageing process in muscle tissue. LMNA encodes the nuclear lamina proteins lamin A/C through alternative splicing, and aberrant splicing of exon 11 leads to the premature ageing disease, Hutchin...
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Main Authors: | Yue Bei Luo, Chalermchai Mitrpant, Russell Johnsen, Vicki Fabian, Merrilee Needham, Sue Fletcher, Steve D. Wilton, Frank L. Mastaglia |
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Other Authors: | University of Western Australia |
Format: | Article |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/32110 |
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Institution: | Mahidol University |
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