A flap motif in human serine hydroxymethyltransferase is important for structural stabilization, ligand binding, and control of product release

A flap motif in human serine hydroxymethyltransferase is important for structural stabilization, ligand binding, and control of product release

© 2019 Ubonprasert et al. Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc. Humancytosolic serine hydroxymethyltransferase (hcSHMT) is a promising target for anticancer chemotherapy and contains a flexible "flap motif" whose function is...

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Bibliographic Details
Main Authors:	Sakunrat Ubonprasert, Juthamas Jaroensuk, Wichai Pornthanakasem, Nuntaporn Kamonsutthipaijit, Peerapong Wongpituk, Pitchayathida Mee-Udorn, Thanyada Rungrotmongkol, Onuma Ketchart, Penchit Chitnumsub, Ubolsree Leartsakulpanich, Pimchai Chaiyen, Somchart Maenpuen
Other Authors:	Vidyasirimedhi Institute of Science and Technology
Format:	Article
Published:	2020
Subjects:	Biochemistry, Genetics and Molecular Biology
Online Access:	https://repository.li.mahidol.ac.th/handle/123456789/50400
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	Mahidol University

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