Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and genetic study

• Main Authors: Rob W. van der Pluijm, Mallika Imwong, Nguyen Hoang Chau, Nhu Thi Hoa, Nguyen Thanh Thuy-Nhien, Ngo Viet Thanh, Podjanee Jittamala, Borimas Hanboonkunupakarn, Kitipumi Chutasmit, Chalermpon Saelow, Ratchadaporn Runjarern, Weerayuth Kaewmok, Rupam Tripura, Thomas J. Peto, Sovann Yok, Seila Suon, Sokunthea Sreng, Sivanna Mao, Savuth Oun, Sovannary Yen, Chanaki Amaratunga, Dysoley Lek, Rekol Huy, Mehul Dhorda, Kesinee Chotivanich, Elizabeth A. Ashley, Mavuto Mukaka, Naomi Waithira, Phaik Yeong Cheah, Richard J. Maude, Roberto Amato, Richard D. Pearson, Sónia Gonçalves, Christopher G. Jacob, William L. Hamilton, Rick M. Fairhurst, Joel Tarning, Markus Winterberg, Dominic P. Kwiatkowski, Sasithon Pukrittayakamee, Tran Tinh Hien, Nicholas PJ Day, Olivo Miotto, Nicholas J. White, Arjen M. Dondorp
• Other Authors: Harvard T.H. Chan School of Public Health
• Format: Article
• Published: 2020
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/51452
• Institution: Mahidol University

© 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4·0 license Background: The emergence and spread of resistance in Plasmodium falciparum malaria to artemisinin combination therapies in the Greater Mekong subregion poses a major threat to malaria c...