Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response

by Zhu, Lei, van der Pluijm, Rob W., Kucharski, Michal, Nayak, Sourav, Tripathi, Jaishree, White, Nicholas J., Day, Nicholas P. J., Faiz, Abul, Phyo, Aung Pyae, Amaratunga, Chanaki, Lek, Dysoley, Ashley, Elizabeth A., Nosten, François, Smithuis, Frank, Ginsburg, Hagai, von Seidlein, Lorenz, Lin, Khin, Imwong, Mallika, Chotivanich, Kesinee, Mayxay, Mayfong, Dhorda, Mehul, Nguyen, Hoang Chau, Nguyen, Thuy Nhien Thanh, Miotto, Olivo, Newton, Paul N., Jittamala, Podjanee, Tripura, Rupam, Pukrittayakamee, Sasithon, Peto, Thomas J., Hien, Tran Tinh, Dondorp, Arjen M., Bozdech, Zbynek
Published 2022

Triple therapy with artemether–lumefantrine plus amodiaquine versus artemether–lumefantrine alone for artemisinin-resistant, uncomplicated falciparum malaria: an open-label, random...

by Thomas J. Peto, Rupam Tripura, James J. Callery, Dysoley Lek, Ho Dang Trung Nghia, Chea Nguon, Nguyen Thi Huyen Thuong, Rob W. van der Pluijm, Nguyen Thi Phuong Dung, Meas Sokha, Vo Van Luong, Le Thanh Long, Yok Sovann, Jureeporn Duanguppama, Naomi Waithira, Richard M. Hoglund, Palang Chotsiri, Nguyen Hoang Chau, Andrea Ruecker, Chanaki Amaratunga, Mehul Dhorda, Olivo Miotto, Richard J. Maude, Huy Rekol, Kesinee Chotivanich, Joel Tarning, Lorenz von Seidlein, Mallika Imwong, Mavuto Mukaka, Nicholas P.J. Day, Tran Tinh Hien, Nicholas J. White, Arjen M. Dondorp
Published 2022

Evolution and expansion of multidrug-resistant malaria in southeast Asia: a genomic epidemiology study

by William L. Hamilton, Roberto Amato, Rob W. van der Pluijm, Christopher G. Jacob, Huynh Hong Quang, Nguyen Thanh Thuy-Nhien, Tran Tinh Hien, Bouasy Hongvanthong, Keobouphaphone Chindavongsa, Mayfong Mayxay, Rekol Huy, Rithea Leang, Cheah Huch, Lek Dysoley, Chanaki Amaratunga, Seila Suon, Rick M. Fairhurst, Rupam Tripura, Thomas J. Peto, Yok Sovann, Podjanee Jittamala, Borimas Hanboonkunupakarn, Sasithon Pukrittayakamee, Nguyen Hoang Chau, Mallika Imwong, Mehul Dhorda, Ranitha Vongpromek, Xin Hui S. Chan, Richard J. Maude, Richard D. Pearson, T. Nguyen, Kirk Rockett, Eleanor Drury, Sónia Gonçalves, Nicholas J. White, Nicholas P. Day, Dominic P. Kwiatkowski, Arjen M. Dondorp, Olivo Miotto
Published 2020

Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and g...

by Rob W. van der Pluijm, Mallika Imwong, Nguyen Hoang Chau, Nhu Thi Hoa, Nguyen Thanh Thuy-Nhien, Ngo Viet Thanh, Podjanee Jittamala, Borimas Hanboonkunupakarn, Kitipumi Chutasmit, Chalermpon Saelow, Ratchadaporn Runjarern, Weerayuth Kaewmok, Rupam Tripura, Thomas J. Peto, Sovann Yok, Seila Suon, Sokunthea Sreng, Sivanna Mao, Savuth Oun, Sovannary Yen, Chanaki Amaratunga, Dysoley Lek, Rekol Huy, Mehul Dhorda, Kesinee Chotivanich, Elizabeth A. Ashley, Mavuto Mukaka, Naomi Waithira, Phaik Yeong Cheah, Richard J. Maude, Roberto Amato, Richard D. Pearson, Sónia Gonçalves, Christopher G. Jacob, William L. Hamilton, Rick M. Fairhurst, Joel Tarning, Markus Winterberg, Dominic P. Kwiatkowski, Sasithon Pukrittayakamee, Tran Tinh Hien, Nicholas PJ Day, Olivo Miotto, Nicholas J. White, Arjen M. Dondorp
Published 2020

Short-course primaquine for the radical cure of Plasmodium vivax malaria: a multicentre, randomised, placebo-controlled non-inferiority trial

by Walter R.J. Taylor, Kamala Thriemer, Lorenz von Seidlein, Prayoon Yuentrakul, Thanawat Assawariyathipat, Ashenafi Assefa, Sarah Auburn, Krisin Chand, Nguyen Hoang Chau, Phaik Yeong Cheah, Le Thanh Dong, Mehul Dhorda, Tamiru Shibru Degaga, Angela Devine, Lenny L. Ekawati, Fahmi Fahmi, Asrat Hailu, Mohammad Anwar Hasanzai, Tran Tinh Hien, Htee Khu, Benedikt Ley, Yoel Lubell, Jutta Marfurt, Hussein Mohammad, Kerryn A. Moore, Mohammad Nader Naddim, Ayodhia Pitaloka Pasaribu, Syahril Pasaribu, Cholrawee Promnarate, Awab Ghulam Rahim, Pasathron Sirithiranont, Hiwot Solomon, Herawati Sudoyo, Inge Sutanto, Ngo Viet Thanh, Nguyen Thi Tuyet-Trinh, Naomi Waithira, Adugna Woyessa, Fazal Yamin Yamin, Arjen Dondorp, Julie A. Simpson, J. Kevin Baird, Nicholas J. White, Nicholas P. Day, Ric N. Price
Published 2020

Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised...

by Rob W. van der Pluijm, Rupam Tripura, Richard M. Hoglund, Aung Pyae Phyo, Dysoley Lek, Akhter ul Islam, Anupkumar R. Anvikar, Parthasarathi Satpathi, Sanghamitra Satpathi, Prativa Kumari Behera, Amar Tripura, Subrata Baidya, Marie Onyamboko, Nguyen Hoang Chau, Yok Sovann, Seila Suon, Sokunthea Sreng, Sivanna Mao, Savuth Oun, Sovannary Yen, Chanaki Amaratunga, Kitipumi Chutasmit, Chalermpon Saelow, Ratchadaporn Runcharern, Weerayuth Kaewmok, Nhu Thi Hoa, Ngo Viet Thanh, Borimas Hanboonkunupakarn, James J. Callery, Akshaya Kumar Mohanty, James Heaton, Myo Thant, Kripasindhu Gantait, Tarapada Ghosh, Roberto Amato, Richard D. Pearson, Christopher G. Jacob, Sónia Gonçalves, Mavuto Mukaka, Naomi Waithira, Charles J. Woodrow, Martin P. Grobusch, Michele van Vugt, Rick M. Fairhurst, Phaik Yeong Cheah, Thomas J. Peto, Lorenz von Seidlein, Mehul Dhorda, Richard J. Maude, Markus Winterberg, Nguyen Thanh Thuy-Nhien, Dominic P. Kwiatkowski, Mallika Imwong, Podjanee Jittamala, Khin Lin, Tin Maung Hlaing, Kesinee Chotivanich, Rekol Huy, Caterina Fanello, Elizabeth Ashley, Mayfong Mayxay, Paul N. Newton, Tran Tinh Hien, Neena Valecha, Frank Smithuis, Sasithon Pukrittayakamee, Abul Faiz, Olivo Miotto, Joel Tarning, Nicholas P.J. Day, Nicholas J. White, Arjen M. Dondorp, Aung Pyae Phyo, Neena Valeche, Nicholas PJ Day
Published 2020

An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples

by Ishag Adam, Mohammad Shafiul Alam, Sisay Alemu, Chanaki Amaratunga, Roberto Amato, Voahangy Andrianaranjaka, Nicholas M. Anstey, Abraham Aseffa, Elizabeth Ashley, Ashenafi Assefa, Sarah Auburn, Bridget E. Barber, Alyssa Barry, Dhelio Batista Pereira, Jun Cao, Nguyen Hoang Chau, Kesinee Chotivanich, Cindy Chu, Arjen M. Dondorp, Eleanor Drury, Diego F. Echeverry, Berhanu Erko, Fe Espino, Rick Fairhurst, Abdul Faiz, María Fernanda Villegas, Qi Gao, Lemu Golassa, Sonia Goncalves, Matthew J. Grigg, Yaghoob Hamedi, Tran Tinh Hien, Ye Htut, Kimberly J. Johnson, Nadira Karunaweera, Wasif Khan, Srivicha Krudsood, Dominic P. Kwiatkowski, Marcus Lacerda, Benedikt Ley, Pharath Lim, Yaobao Liu, Alejandro Llanos-Cuentas, Chanthap Lon, Tatiana Lopera-Mesa, Jutta Marfurt, Pascal Michon, Olivo Miotto, Rezika Mohammed, Ivo Mueller, Chayadol Namaik-larp, Paul N. Newton, Thuy Nhien Nguyen, Francois Nosten, Rintis Noviyanti, Zuleima Pava, Richard D. Pearson, Beyene Petros, Aung P. Phyo, Ric N. Price, Sasithon Pukrittayakamee, Awab Ghulam Rahim, Milijaona Randrianarivelojosia, Julian C. Rayner, Angela Rumaseb, Sasha V. Siegel, Victoria J. Simpson, Kamala Thriemer, Alberto Tobon-Castano, Hidayat Trimarsanto, Marcelo Urbano Ferreira, Ivan D. Vélez, Sonam Wangchuk, Thomas E. Wellems, Nicholas J. White, Timothy William, Maria F. Yasnot, Daniel Yilma
Published 2022

Genetic surveillance in the greater mekong subregion and south asia to support malaria control and elimination

by Christopher G. Jacob, Nguyen Thuy-Nhien, Mayfong Mayxay, Richard J. Maude, Huynh Hong Quang, Bouasy Hongvanthong, Viengxay Vanisaveth, Thang Ngo Duc, Huy Rekol, Rob van der Pluijm, Lorenz von Seidlein, Rick Fairhurst, François Nosten, Md Amir Hossain, Naomi Park, Scott Goodwin, Pascal Ringwald, Keobouphaphone Chindavongsa, Paul Newton, Elizabeth Ashley, Sonexay Phalivong, Rapeephan Maude, Rithea Leang, Cheah Huch, Le Thanh Dong, Kim Tuyen Nguyen, Tran Minh Nhat, Tran Tinh Hien, Hoa Nguyen, Nicole Zdrojewski, Sara Canavati, Abdullah Abu Sayeed, Didar Uddin, Caroline Buckee, Caterina I. Fanello, Marie Onyamboko, Thomas Peto, Rupam Tripura, Chanaki Amaratunga, Aung Myint Thu, Gilles Delmas, Jordi Landier, Daniel M. Parker, Nguyen Hoang Chau, Dysoley Lek, Seila Suon, James Callery, Podjanee Jittamala, Borimas Hanboonkunupakarn, Sasithon Pukrittayakamee, Aung Pyae Phyo, Frank Smithuis, Khin Lin, Myo Thant, Tin Maung Hlaing, Parthasarathi Satpathi, Sanghamitra Satpathi, Prativa K. Behera, Amar Tripura, Subrata Baidya, Neena Valecha, Anupkumar R. Anvikar, Akhter Ul Islam, Abul Faiz, Chanon Kunasol, Eleanor Drury, Mihir Kekre, Mozam Ali, Katie Love, Shavanthi Rajatileka, Anna E. Jeffreys, Kate Rowlands, Christina S. Hubbart, Mehul Dhorda, Ranitha Vongpromek, Namfon Kotanan, Phrutsamon Wongnak, Jacob Almagro Garcia, Richard D. Pearson, Cristina V. Ariani, Thanat Chookajorn, Cinzia Malangone, T. Nguyen, Jim Stalker, Ben Jeffery, Jonathan Keatley, Kimberly J. Johnson, Dawn Muddyman, Xin Hui S. Chan, John Sillitoe, Roberto Amato, Victoria Simpson, Sonia Gonçalves, Kirk Rockett, Nicholas P. Day, Arjen M. Dondorp, Dominic P. Kwiatkowski, Olivo Miotto
Published 2022