High sensitivity methods to quantify chloroquine and its metabolite in human blood samples using LC-MS/MS

by Karnrawee Kaewkhao, Kesinee Chotivanich, Markus Winterberg, Nicholas Pj Day, Joel Tarning, Daniel Blessborn
Published 2020

Assessment of the amino acid profile in Thai patients with type 2 diabetes mellitus using liquid chromatography-mass spectrometry

by Natthida Sriboonvorakul, Wirichada Pan-Ngum, Kittiyod Poovorawan, Markus Winterberg, Joel Tarning, Sant Muangnoicharoen
Published 2022

Effect of antiretroviral therapy on plasma concentrations of chloroquine and desethyl-chloroquine

by Matthew M. Ippolito, Jeffrey M. Jacobson, Michael M. Lederman, Markus Winterberg, Joel Tarning, Theresa A. Shapiro, Charles Flexner
Published 2019

Mass spectrometry-based proteomic techniques to identify cerebrospinal fluid biomarkers for diagnosing suspected central nervous system infections. A systematic review

by Tehmina Bharucha, Bevin Gangadharan, Abhinav Kumar, Xavier de Lamballerie, Paul N. Newton, Markus Winterberg, Audrey Dubot-Pérès, Nicole Zitzmann
Published 2020

Adherence and Population Pharmacokinetic Properties of Amodiaquine When Used for Seasonal Malaria Chemoprevention in African Children

by Junjie Ding, Matthew E. Coldiron, Bachir Assao, Ousmane Guindo, Daniel Blessborn, Markus Winterberg, Rebecca F. Grais, Alena Koscalova, Celine Langendorf, Joel Tarning
Published 2020

Differential impact of nevirapine on artemether-lumefantrine pharmacokinetics in individuals stratified by CYP2B6 c.516G>T genotypes

by T. Abdullahi Sa'ad, Julius O. Soyinka, Adeniyi Olagunju, Rahman A. Bolarinwa, Olusola J. Olarewaju, Moji T. Bakare-Odunola, Markus Winterberg, Joel Tarning, Andrew Owen, Saye Khoo
Published 2020

CYP2B6*6 Genotype Specific Differences in Artemether-Lumefantrine Disposition in Healthy Volunteers

by Sa'ad T. Abdullahi, Julius O. Soyinka, Adeniyi Olagunju, Rahman A. Bolarinwa, Olusola J. Olarewaju, Moji T. Bakare-Odunola, Markus Winterberg, Joel Tarning, Andrew Owen, Saye Khoo
Published 2020

Drug interactions between dolutegravir and artemether-lumefantrine or artesunate-amodiaquine

by Stephen I. Walimbwa, Mohammed Lamorde, Catriona Waitt, Julian Kaboggoza, Laura Else, Pauline Byakika-Kibwika, Alieu Amara, Joshua Gini, Markus Winterberg, Justin Chiong, Joel Tarning, Saye H. Khoo
Published 2020

Poor response to artesunate treatment in two patients with severe malaria on the Thai-Myanmar border

by Aung Pyae Phyo, Kyaw Kyaw Win, Aung Myint Thu, Lei Lei Swe, Htike Htike, Candy Beau, Kanlaya Sriprawat, Markus Winterberg, Stephane Proux, Mallika Imwong, Elizabeth A. Ashley, Francois Nosten
Published 2019

Sequential open-label study of the safety, tolerability, and pharmacokinetic interactions between dihydroartemisinin-piperaquine and mefloquine in healthy Thai adults

by Borimas Hanboonkunupakarn, Rob W. Van Der Pluijm, Richard Hoglund, Sasithon Pukrittayakamee, Markus Winterberg, Mavuto Mukaka, Naomi Waithira, Kesinee Chotivanich, Pratap Singhasivanon, Nicholas J. White, Arjen M. Dondorp, Joel Tarning, Podjanee Jittamala
Published 2020

Characterization of the ATP4 ion pump in Toxoplasma gondii

by Adele M. Lehane, Adelaide S.M. Dennis, Katherine O. Bray, Dongdi Li, Esther Rajendran, James M. McCoy, Hillary M. McArthur, Markus Winterberg, Farid Rahimi, Christopher J. Tonkin, Kiaran Kirk, Giel G. Van Dooren
Published 2020

Identifying the Components of Acidosis in Patients with Severe Plasmodium falciparum Malaria Using Metabolomics

by Stije J. Leopold, Aniruddha Ghose, Erik L. Allman, Hugh W.F. Kingston, Amir Hossain, Asok Kumar Dutta, Katherine Plewes, Kesinee Chotivanich, Nicholas P.J. Day, Joel Tarning, Markus Winterberg, Nicholas J. White, Manuel Llinás, Arjen M. Dondorp
Published 2020

Safety, Pharmacokinetics, and Mosquito-Lethal Effects of Ivermectin in Combination With Dihydroartemisinin-Piperaquine and Primaquine in Healthy Adult Thai Subjects

by Kevin C. Kobylinski, Podjanee Jittamala, Borimas Hanboonkunupakarn, Sasithon Pukrittayakamee, Kanchana Pantuwatana, Siriporn Phasomkusolsil, Silas A. Davidson, Markus Winterberg, Richard M. Hoglund, Mavuto Mukaka, Rob W. van der Pluijm, Arjen Dondorp, Nicholas P.J. Day, Nicholas J. White, Joel Tarning
Published 2020

Prospective Clinical and Molecular Evaluation of Potential Plasmodium ovale curtisi and wallikeri Relapses in a High-transmission Setting

by Mirjam Groger, Luzia Veletzky, Albert Lalremruata, Chiara Cattaneo, Johannes Mischlinger, Rella Manego Zoleko, Johanna Kim, Anna Klicpera, Elias L. Meyer, Daniel Blessborn, Markus Winterberg, Ayola A. Adegnika, Selidji T. Agnandji, Peter G. Kremsner, Benjamin Mordmüller, Ghyslain Mombo-Ngoma, Hans Peter Fuehrer, Michael Ramharter
Published 2020

Comparison of the cumulative efficacy and safety of chloroquine, artesunate, and chloroquine-primaquine in plasmodium vivax malaria

by Cindy S. Chu, Aung Pyae Phyo, Khin Maung Lwin, Htun Htun Win, Thida San, Aye Aye Aung, Rattanaporn Raksapraidee, Verena I. Carrara, Germana Bancone, James Watson, Kerryn A. Moore, Jacher Wiladphaingern, Stéphane Proux, Kanlaya Sriprawat, Markus Winterberg, Phaik Yeong Cheah, Amy L. Chue, Joel Tarning, Mallika Imwong, François Nosten, Nicholas J. White
Published 2019

Pooled multicenter analysis of cardiovascular safety and population pharmacokinetic properties of piperaquine in african patients with uncomplicated falciparum malaria

by Thanaporn Wattanakul, Bernhards Ogutu, Abdunoor M. Kabanywanyi, Kwaku Poku Asante, Abraham Oduro, Alex Adjei, Ali Sie, Esperanca Sevene, Eusebio MacEte, Guillaume Compaore, Innocent Valea, Isaac Osei, Markus Winterberg, Margaret Gyapong, Martin Adjuik, Salim Abdulla, Seth Owusu-Agyei, Nicholas J. White, Nicholas P.J. Day, Halidou Tinto, Rita Baiden, Fred Binka, Joel Tarning
Published 2020

Combining antimalarial drugs and vaccine for malaria elimination campaigns: a randomized safety and immunogenicity trial of RTS,S/AS01 administered with dihydroartemisinin, piperaq...

by Lorenz von Seidlein, Borimas Hanboonkunupakarn, Podjanee Jittamala, Pongphaya Pongsuwan, Kesinee Chotivanich, Joel Tarning, Richard M. Hoglund, Markus Winterberg, Mavuto Mukaka, Pimnara Peerawaranun, Pasathorn Sirithiranont, Zoe Doran, Christian F. Ockenhouse, Karen Ivinson, Cynthia Lee, Ashley J. Birkett, David C. Kaslow, Pratap Singhasivanon, Nicholas P.J. Day, Arjen M. Dondorp, Nicholas J. White, Sasithon Pukrittayakamee
Published 2020

Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and g...

by Rob W. van der Pluijm, Mallika Imwong, Nguyen Hoang Chau, Nhu Thi Hoa, Nguyen Thanh Thuy-Nhien, Ngo Viet Thanh, Podjanee Jittamala, Borimas Hanboonkunupakarn, Kitipumi Chutasmit, Chalermpon Saelow, Ratchadaporn Runjarern, Weerayuth Kaewmok, Rupam Tripura, Thomas J. Peto, Sovann Yok, Seila Suon, Sokunthea Sreng, Sivanna Mao, Savuth Oun, Sovannary Yen, Chanaki Amaratunga, Dysoley Lek, Rekol Huy, Mehul Dhorda, Kesinee Chotivanich, Elizabeth A. Ashley, Mavuto Mukaka, Naomi Waithira, Phaik Yeong Cheah, Richard J. Maude, Roberto Amato, Richard D. Pearson, Sónia Gonçalves, Christopher G. Jacob, William L. Hamilton, Rick M. Fairhurst, Joel Tarning, Markus Winterberg, Dominic P. Kwiatkowski, Sasithon Pukrittayakamee, Tran Tinh Hien, Nicholas PJ Day, Olivo Miotto, Nicholas J. White, Arjen M. Dondorp
Published 2020

Understanding the benefits and burdens associated with a malaria human infection study in Kenya: experiences of study volunteers and other stakeholders

by Primus Che Chi, Esther Awuor Owino, Irene Jao, Fredrick Olewe, Bernhards Ogutu, Philip Bejon, Melissa Kapulu, Dorcas Kamuya, Vicki Marsh, Abdirahman I. Abdi, Yonas Abebe, Agnes Audi, Peter Billingsley, Peter C. Bull, Mainga Hamaluba, Zaydah de Laurent, Susanne H. Hodgson, Stephen Hoffman, Eric James, Gathoni Kamuyu, Silvia Kariuki, Nelson Kibinge, Rinter Kimathi, Sam Kinyanjui, Cheryl Kivisi, Nelly Koskei, Mallika Imwong, Brett Lowe, Johnstone Makale, Kevin Marsh, Khadija Said Mohammed, Moses Mosobo, Sean C. Murphy, Linda Murungi, Jennifer Musyoki, Michelle Muthui, Jedidah Mwacharo, Daniel Mwanga, Joyce Mwongeli, Francis Ndungu, Maureen Njue, Patricia Njuguna, George Nyangweso, Domitila Kimani, Joyce M. Ngoi, Janet Musembi, Omar Ngoto, Edward Otieno, Faith Osier, James Oloo, Donwilliams Omuoyo, John Ongecha, Martin O. Ongas, Michael Ooko, Jimmy Shangala, Betty Kim Lee Sim, Joel Tarning, James Tuju, Juliana Wambua, Thomas N. Williams, Markus Winterberg
Published 2022

Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised...

by Rob W. van der Pluijm, Rupam Tripura, Richard M. Hoglund, Aung Pyae Phyo, Dysoley Lek, Akhter ul Islam, Anupkumar R. Anvikar, Parthasarathi Satpathi, Sanghamitra Satpathi, Prativa Kumari Behera, Amar Tripura, Subrata Baidya, Marie Onyamboko, Nguyen Hoang Chau, Yok Sovann, Seila Suon, Sokunthea Sreng, Sivanna Mao, Savuth Oun, Sovannary Yen, Chanaki Amaratunga, Kitipumi Chutasmit, Chalermpon Saelow, Ratchadaporn Runcharern, Weerayuth Kaewmok, Nhu Thi Hoa, Ngo Viet Thanh, Borimas Hanboonkunupakarn, James J. Callery, Akshaya Kumar Mohanty, James Heaton, Myo Thant, Kripasindhu Gantait, Tarapada Ghosh, Roberto Amato, Richard D. Pearson, Christopher G. Jacob, Sónia Gonçalves, Mavuto Mukaka, Naomi Waithira, Charles J. Woodrow, Martin P. Grobusch, Michele van Vugt, Rick M. Fairhurst, Phaik Yeong Cheah, Thomas J. Peto, Lorenz von Seidlein, Mehul Dhorda, Richard J. Maude, Markus Winterberg, Nguyen Thanh Thuy-Nhien, Dominic P. Kwiatkowski, Mallika Imwong, Podjanee Jittamala, Khin Lin, Tin Maung Hlaing, Kesinee Chotivanich, Rekol Huy, Caterina Fanello, Elizabeth Ashley, Mayfong Mayxay, Paul N. Newton, Tran Tinh Hien, Neena Valecha, Frank Smithuis, Sasithon Pukrittayakamee, Abul Faiz, Olivo Miotto, Joel Tarning, Nicholas P.J. Day, Nicholas J. White, Arjen M. Dondorp, Aung Pyae Phyo, Neena Valeche, Nicholas PJ Day
Published 2020