Interference on cytosolic DNA activation attenuates sepsis severity: Experiments on cyclic GMP–AMP synthase (cGAS) deficient mice
Although the enhanced responses against serum cell-free DNA (cfDNA) in cases of sepsis—a life-threatening organ dysfunction due to systemic infection—are understood, the influence of the cytosolic DNA receptor cGAS (cyclic guanosine monophosphate–adenosine monophosphate (GMP– AMP) synthase) on sepsi...
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| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Published: |
2022
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| Subjects: | |
| Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/75983 |
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| Institution: | Mahidol University |