Single-Cell RNA-seq Reveals Angiotensin-Converting Enzyme 2 and Transmembrane Serine Protease 2 Expression in TROP2+ Liver Progenitor Cells: Implications in Coronavirus Disease 201...

by Seow, Justine Jia Wen, Pai, Rhea, Mishra, Archita, Shepherdson, Edwin, Lim, Tony Kiat Hon, Goh, Brian K. P., Chan, Jerry K. Y., Chow, Pierce K. H., Ginhoux, Florent, DasGupta, Ramanuj, Sharma, Ankur
Published 2022

Microfluidic enrichment for the single cell analysis of circulating tumor cells

by Yeo, Trifanny, Tan, Swee Jin, Lim, Chew Leng, Lau, Dawn Ping Xi, Chua, Yong Wei, Krisna, Sai Sakktee, Iyer, Gopal, Tan, Gek San, Lim, Tony Kiat Hon, Tan, Daniel SW, Lim, Wan-Teck, Lim, Chwee Teck
Published 2022

Conditional knockout of hypoxia-inducible factor 1-alpha in tumor-infiltrating neutrophils protects against pancreatic ductal adenocarcinoma

by Sieow, Je Lin, Leong, Penny Hweixian, Gun, Sin Yee, Tan, Ling Qiao, Duan, Kaibo, Yeong, Joe Poh Sheng, Pang, Angela, Lim, Diana, Toh, Han Chong, Lim, Tony Kiat Hon, Engleman, Edgar, Rotzschke, Olaf, Ng, Lai Guan, Chen, Jinmiao, Tan, Suet Mien, Wong, Siew Cheng
Published 2023

Conditional Knockout of Hypoxia-Inducible Factor 1-Alpha in Tumor-Infiltrating Neutrophils Protects against Pancreatic Ductal Adenocarcinoma

by Sieow, Je Lin, Penny, Hweixian Leong, Gun, Sin Yee, Tan, Ling Qiao, Duan, Kaibo, Yeong, Joe Poh Sheng, Pang, Angela, Lim, Diana, Toh, Han Chong, Lim, Tony Kiat Hon, Engleman, Edgar, Rotzschke, Olaf, Ng, Lai Guan, Chen, Jinmao, Tan, Suet Mien, Wong, Siew Cheng
Published 2023

The spatial organization of intra-tumour heterogeneity and evolutionary trajectories of metastases in hepatocellular carcinoma

by Zhai, Weiwei, Choo, Su-Pin, Khor, Chiea Chuen, Lim, Tony Kiat-Hon, Zhang, Tong, Phang, Su-Ting, Tiang, Zenia, Guan, Peiyong, Ng, Ming-Hwee, Lim, Jia Qi, Yao, Fei, Li, Zheng, Ng, Poh Yong, Yan, Jie, Goh, Brian K., Chung, Alexander Yaw-Fui, Soon, Wendy Wei-Jia, Sung, Ken Wing-Kin, Foo, Roger Sik-Yin, Chow, Pierce Kah-Hoe
Published 2018

Methionine is a metabolic dependency of tumor-initiating cells

by Wang, Zhenxun, Yip, Lian Yee, Lee, Jane Jia Hui, Wu, Zhengwei, Chew, Hui Yi, Chong, William Pooi Kiat, Teo, Chin Chye, Ang, Heather Yin-Kuan, Peh, Esther Kai Lay, Yuan, Ju, Ma, Siming, Choo, Kimberly Li Shi, Basri, Nurhidayah, Jiang, Xia, Yu, Qiang, Hillmer, Axel M., Lim, Wan Teck, Lim, Tony Kiat Hon, Takano, Angela, Tan, Eng Huat, Tan, Daniel Shao Weng, Ho, Ying Swan, Lim, Bing, Tam, Wai Leong
Published 2021

Complementary Sequential Circulating Tumor Cell (CTC) and Cell-Free Tumor DNA (ctDNA) Profiling Reveals Metastatic Heterogeneity and Genomic Changes in Lung Cancer and Breast Cance...

by Kong, Say Li, Liu, Xingliang, Tan, Swee Jin, Tai, Joyce A, Phua, Ler Yee, Poh, Huay Mei, Yeo, Trifanny, Chua, Yong Wei, Haw, Yu Xuan, Ling, Wen Huan, Ng, Raymond Chee Hui, Tan, Tira J, Loh, Kiley Wei Jen, Tan, Daniel Shao-Weng, Ng, Quan Sing, Ang, Mei Kim, Toh, Chee Keong, Lee, Yi Fang, Lim, Chwee Teck, Lim, Tony Kiat Hon, Hillmer, Axel M, Yap, Yoon Sim, Lim, Wan-Teck
Published 2022

Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma

by Sharma, Ankur, Seow, Justine Jia Wen, Dutertre, Charles-Antoine, Pai, Rhea, Bleriot, Camille, Mishra, Archita, Wong, Regina Men Men, Singh, Gurmit Singh Naranjan, Sudhagar, Samydurai, Khalilnezhad, Shabnam, Erdal, Sergio, Teo, Hui Min, Khalilnezhad, Ahad, Chakarov, Svetoslav, Lim, Tony Kiat Hon, Fui, Alexander Chung Yaw, Chieh, Alfred Kow Wei, Chung, Cheow Peng, Bonney, Glenn Kunnath, Goh, Brian Kim-Poh, Chan, Jerry KY, Chow, Pierce KH, Ginhoux, Florent, DasGupta, Ramanuj
Published 2021

Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing

by Nahar, Rahul, Zhai, Weiwei, Zhang, Tong, Takano, Angela, Khng, Alexis J., Lee, Yin Yeng, Liu, Xingliang, Lim, Chong Hee, Koh, Tina P. T., Aung, Zaw Win, Lim, Tony Kiat Hon, Veeravalli, Lavanya, Yuan, Ju, Teo, Audrey S. M., Chan, Cheryl X., Poh, Huay Mei, Chua, Ivan M. L., Liew, Audrey Ann, Lau, Dawn Ping Xi, Kwang, Xue Lin, Toh, Chee Keong, Lim, Wan-Teck, Lim, Bing, Tam, Wai Leong, Tan, Eng-Huat, Hillmer, Axel M., Tan, Daniel S. W.
Published 2018

Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease

by Mulder, Kevin, Patel, Amit Ashok, Kong, Wan Ting, Piot, Cecile, Halitzki, Evelyn, Dunsmore, Garett, Khalilnezhad, Shabnam, Irac, Sergio Erdal, Dubuisson, Agathe, Chevrier, Marion, Zhang, Xiao Meng, Tam, John Kit Chung, Lim, Tony Kiat Hon, Wong, Regina Men Men, Pai, Rhea, Khalil, Ahmed Ibrahim Samir, Chow, Pierce Kah Hoe, Wu, Suny Z, Al-Eryani, Ghamdan, Roden, Daniel, Swarbrick, Alexander, Chan, Jerry Kok Yen, Albani, Salvatore, Derosa, Lisa, Zitvogel, Laurence, Sharma, Ankur, Chen, Jinmiao, Silvin, Aymeric, Bertoletti, Antonio, Bleriot, Camille, Dutertre, Charles-Antoine, Ginhoux, Florent
Published 2022

Multi-region sampling with paired sample sequencing analyses reveals sub-groups of patients with novel patient-specific dysregulation in Hepatocellular Carcinoma

by Jeon, Ah-Jung, Teo, Yue-Yang, Sekar, Karthik, Chong, Shay Lee, Wu, Lingyan, Chew, Sin-Chi, Chen, Jianbin, Kendarsari, Raden Indah, Lai, Hannah, Ling, Wen Huan, Kaya, Neslihan Arife, Lim, Jia Qi, Ramasamy, Adaikalavan, Oguz, Gokce, Chung, Alexander Yaw-Fui, Chan, Chung Yip, Cheow, Peng-Chung, Kam, Juinn Huar, Madhavan, Krishnakumar, Kow, Alfred, Ganpathi, Iyer Shridhar, Lim, Tony Kiat Hon, Leow, Wei-Qiang, Loong, Shihleone, Loh, Tracy Jiezhen, Wan, Wei Keat, Soon, Gwyneth Shook Ting, Pang, Yin Huei, Yoong, Boon Koon, Ong, Diana Bee-Lan, Lim, Jasmine, de Villa, Vanessa H., dela Cruz, Rouchelle D., Chanwat, Rawisak, Thammasiri, Jidapa, Bonney, Glenn K., Goh, Brian K. P., Tucker-Kellogg, Greg, Foo, Roger Sik Yin, Chow, Pierce K. H.
Published 2023

Dynamic phenotypic heterogeneity and the evolution of multiple RNA subtypes in hepatocellular carcinoma: the PLANET study

by Zhai, Weiwei, Lai, Hannah, Kaya, Neslihan Arife, Chen, Jianbin, Yang, Hechuan, Lu, Bingxin, Lim, Jia Qi, Ma, Siming, Chew, Sin Chi, Chua, Khi Pin, Alvarez, Jacob Josiah Santiago, Chen, Pauline Jieqi, Chang, Mei Mei, Wu, Lingyan, Goh, Brian K. P., Chung, Alexander Yaw-Fui, Chan, Chung Yip, Cheow, Peng Chung, Lee, Ser Yee, Kam, Juinn Huar, Kow, Alfred Wei-Chieh, Ganpathi, Iyer Shridhar, Chanwat, Rawisak, Thammasiri, Jidapa, Yoong, Boon Koon, Ong, Diana Bee-Lan, de Villa, Vanessa H., Dela Cruz, Rouchelle D., Loh, Tracy Jiezhen, Wan, Wei Keat, Zeng, Zeng, Skanderup, Anders Jacobsen, Pang, Yin Huei, Madhavan, Krishnakumar, Lim, Tony Kiat-Hon, Bonney, Glenn, Leow, Wei Qiang, Chew, Valerie, Dan, Yock Young, Tam, Wai Leong, Toh, Han Chong, Foo, Roger Sik-Yin, Chow, Pierce Kah-Hoe
Published 2023