Structure of a mutagen from roasted seeds of Moringa oleifera

• Main Authors: Villasenor, Irene M, Finch, Paul, Lim-Sylianco, Clara, Dayrit, Fabian M
• Format: text
• Published: Archīum Ateneo 1989
• Subjects: erythrocytes; dimethyl sulfoxide; micronucleus tests; moringa oleifera; mutagens; seeds; solvents; spectrum analysis; tetracycline; positive control; Biochemistry; Chemistry
• Online Access: https://archium.ateneo.edu/chemistry-faculty-pubs/114; https://academic.oup.com/carcin/article-abstract/10/6/1085/404083
• Institution: Ateneo De Manila University

A mutagenic compound was isolated from roasted seeds of Moringa oleifera Lam. Its structure has been elucidated by spectral analysis as 4(α-L-rhamnosyloxy)phenylacetonitrile. The results of the Micronucleus Test, an in vivo method, showed that the number of micronucleated polychromatic erythrocytes...