Weak affinity chromatography for evaluation of stereoisomers in early drug discovery

Weak affinity chromatography for evaluation of stereoisomers in early drug discovery

In early drug discovery (e.g., in fragment screening), recognition of stereoisomeric structures is valuable and guides medicinal chemists to focus only on useful configurations. In this work, we concurrently screened mixtures of stereoisomers and estimated their affinities to a protein target (throm...

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書目詳細資料
Main Authors:	Duong-Thi, M.-D., Bergstrom, M., Fex, T., Svensson, S., Ohlson, S., Isaksson, R.
其他作者:	School of Biological Sciences
格式:	Article
語言:	English
出版:	2013
主題:	DRNTU::Science::Biological sciences::Microbiology
在線閱讀:	https://hdl.handle.net/10356/101288 http://hdl.handle.net/10220/16729
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!
機構:	Nanyang Technological University
語言:	English

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