The stress granule protein G3BP1 binds viral dsRNA and RIG-I to enhance interferon-β response

The stress granule protein G3BP1 binds viral dsRNA and RIG-I to enhance interferon-β response

RIG-I senses viral RNA in the cytosol and initiates host innate immune response by triggering the production of type 1 interferon. A recent RNAi knockdown screen yielded close to hundred host genes whose products affected viral RNA-induced IFN-β production and highlighted the complexity of the antiv...

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Bibliographic Details
Main Authors: Kim, Susana Soo-Yeon, Sze, Lynette, Lam, Kong-Peng
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2019
Subjects:
Innate Immunity
Viral Immunology
Science::Biological sciences
Online Access:https://hdl.handle.net/10356/106405
http://hdl.handle.net/10220/49627
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/106405
http://hdl.handle.net/10220/49627

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