The stress granule protein G3BP1 binds viral dsRNA and RIG-I to enhance interferon-β response
RIG-I senses viral RNA in the cytosol and initiates host innate immune response by triggering the production of type 1 interferon. A recent RNAi knockdown screen yielded close to hundred host genes whose products affected viral RNA-induced IFN-β production and highlighted the complexity of the antiv...
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| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/106405 http://hdl.handle.net/10220/49627 |
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| Institution: | Nanyang Technological University |
| Language: | English |