MicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression
Polycomb group protein Ezh2 is a histone H3 Lys-27 histone methyltransferase orchestrating an extensive epigenetic regulatory program. Several nervous system-specific genes are known to be repressed by Ezh2 in stem cells and derepressed during neuronal differentiation. However, the molecular mechani...
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Main Authors: | Neo, Wen Hao, Yap, Karen, Lee, Suet Hoay, Looi, Liang Sheng, Khandelia, Piyush, Neo, Sheng Xiong, Makeyev, Eugene V., Su, I-hsin |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2015
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/106735 http://hdl.handle.net/10220/25120 |
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Institution: | Nanyang Technological University |
Language: | English |
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