MicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression

Polycomb group protein Ezh2 is a histone H3 Lys-27 histone methyltransferase orchestrating an extensive epigenetic regulatory program. Several nervous system-specific genes are known to be repressed by Ezh2 in stem cells and derepressed during neuronal differentiation. However, the molecular mechani...

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Bibliographic Details
Main Authors: Neo, Wen Hao, Yap, Karen, Lee, Suet Hoay, Looi, Liang Sheng, Khandelia, Piyush, Neo, Sheng Xiong, Makeyev, Eugene V., Su, I-hsin
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2015
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Online Access:https://hdl.handle.net/10356/106735
http://hdl.handle.net/10220/25120
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Institution: Nanyang Technological University
Language: English

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