Intramolecular C-N bond formation under metal-free conditions : synthesis of indolizines

• Main Authors: Wu, Junliang, Leng, Wei Lin, Liao, Hongze, Mai Hoang, Kim Le, Liu, Xue-Wei
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Chemistry::Physical chemistry::Molecular structure and bonding
• Online Access: https://hdl.handle.net/10356/107165; http://hdl.handle.net/10220/25408; http://dx.doi.org/10.1002/asia.201403400
• Institution: Nanyang Technological University

Polysubstituted indolizine derivatives are constructed via intramolecular C--N bond formation/C--H bond cleavage under metal-free conditions. These methods offer straightforward pathways to transform pyridyl chalcones into a variety of indolizines.