Carbene-catalyzed LUMO activation of alkyne esters for access to functional pyridines

• Main Authors: Mou, Chengli, Wu, Jichang, Huang, Zhijian, Sun, Jun, Jin, Zhichao, Chi, Robin Yonggui
• 其他作者: School of Physical and Mathematical Sciences
• 格式: Article
• 語言: English
• 出版: 2020
• 主題: Science::Chemistry::Organic chemistry; Pyridines; NHC Catalyst
• 在線閱讀: https://hdl.handle.net/10356/138302

A carbene-catalyzed LUMO activation of a,b-unsaturated alkyne esters is reported. This catalytic process allows for effective reactions of alkyne esters with enamides to synthesize functional pyridines via simple protocols. A previously unexplored unsaturated alkyne acyl azolium intermediate is invo...