Carbene-catalyzed LUMO activation of alkyne esters for access to functional pyridines

• المؤلفون الرئيسيون: Mou, Chengli, Wu, Jichang, Huang, Zhijian, Sun, Jun, Jin, Zhichao, Chi, Robin Yonggui
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science::Chemistry::Organic chemistry; Pyridines; NHC Catalyst
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/138302
• المؤسسة: Nanyang Technological University

A carbene-catalyzed LUMO activation of a,b-unsaturated alkyne esters is reported. This catalytic process allows for effective reactions of alkyne esters with enamides to synthesize functional pyridines via simple protocols. A previously unexplored unsaturated alkyne acyl azolium intermediate is invo...