Structural and dynamics study of G-rich sequences relevant to genomic disorders
Aberrant DNA repeat expansions have been linked to several (> 30) neurological and muscular disorders. In this dissertation, we present structural studies performed on two such repeat sequences GGGGCC and TGG using Nuclear Magnetic Resonance Spectroscopy (NMR) and other biophysical techniques....
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2020
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| Online Access: | https://hdl.handle.net/10356/141701 |
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| Institution: | Nanyang Technological University |
| Language: | English |