Kinomic profile in patient-derived glioma cells during hypoxia reveals c-MET-PI3K dependency for adaptation
Hypoxic microenvironment is a hallmark of solid tumors, especially glioblastoma. The strong reliance of glioma-propagating cells (GPCs) on hypoxia-induced survival advantages is potentially exploitable for drug development. Methods: To identify key signaling pathways for hypoxia adaptation by patien...
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Main Authors: | Cheng, Hong Sheng, Marvalim, Charlie, Zhu, Pengcheng, Law, Daniel Cheng Lui, Low, Jeremy Zhi Yan, Chong, Yuk Kien, Ang, Beng Ti, Tang, Carol, Tan, Nguan Soon |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2021
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/153593 |
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Institution: | Nanyang Technological University |
Language: | English |
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