Genetic modulators of Plasmodium falciparum parasites asexual fitness and resistance to clinical and preclinical compounds
Emergence of malarial Plasmodium falciparum KEL1/PLA1 co-lineage in Southeast Asia caused the failure of dihydroartemisin+piperaquine (DHA+PPQ). PfKelch (k13) C580Y mutation and plasmepsins 2/3 gene (pm2/3) amplification, markers of DHA and PPQ resistance respectively, are hallmarks of KEL1/PLA1 par...
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| Format: | Final Year Project |
| Language: | English |
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Nanyang Technological University
2023
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| Online Access: | https://hdl.handle.net/10356/167504 |
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| Institution: | Nanyang Technological University |
| Language: | English |