Phase-separating peptide coacervates with programmable material properties for universal intracellular delivery of macromolecules
Phase-separating peptides (PSPs) self-assembling into coacervate microdroplets (CMs) are a promising class of intracellular delivery vehicles that can release macromolecular modalities deployed in a wide range of therapeutic treatments. However, the molecular grammar governing intracellular uptake a...
Saved in:
Main Authors: | Sun, Yue, Wu, Xi, Li, Jianguo, Radiom, Milad, Mezzenga, Raffaele, Verma, Chandra Shekhar, Yu, Jing, Miserez, Ali |
---|---|
Other Authors: | School of Materials Science and Engineering |
Format: | Article |
Language: | English |
Published: |
2025
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/182044 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
Similar Items
-
Investigating peptide sequence variations for ‘double-click’ stapled p53 peptides
by: Lau, Yu Heng, et al.
Published: (2016) -
Biomimetic peptide coacervates for intracellular delivery and release of biomacromolecules
by: Sun, Yue
Published: (2022) -
Elucidating intracellular trafficking of His-rich peptide coacervates
by: Liu, Yiting
Published: (2024) -
Cellular uptake of phase-separating peptide coacervates
by: Shebanova, Anastasia, et al.
Published: (2024) -
Monitoring disassembly and cargo release of phase-separated peptide coacervates with native mass spectrometry
by: Cerrato, Carmine P., et al.
Published: (2023)