Mechanism of sensing antimicrobial peptides by bacteria : towards a structural understanding ; LPS-bound structures of designed peptides : effects of incorporation of β-turn nucleating amino acids (D-Pro and Asn).
The Aps system, consisting of a transmembrane sensor protein ApsS and two cytosolic ApsX and ApsR, is responsible for antimicrobial peptides (AMPs) resistance mechanism in Gram-positive bacteria. The ApsS acts as a sensor to have direct interactions with AMPs through its extra-cellular loop connecte...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2010
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| Online Access: | http://hdl.handle.net/10356/39735 |
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| Institution: | Nanyang Technological University |
| Language: | English |