Co-delivery of TGF-β3 and COL I-targeting shRNA with adenoviral and lentiviral vectors for COL I-surpressed in vitro chondrogenesis

• 主要作者: M. K. Mohamed Idris
• 其他作者: Wang Dongan
• 格式: Final Year Project
• 語言: English
• 出版: 2011
• 主題: DRNTU::Science::Biological sciences::Microbiology::Virology; DRNTU::Science::Medicine::Tissue engineering
• 在線閱讀: http://hdl.handle.net/10356/45690
• 機構: Nanyang Technological University

Cartilage degeneration poses a challenge to clinicians in spite of the various therapies that have been developed for its treatment. Cell-based therapy is promising due to its ability to restore the structure and function of the native cartilage as much as possible. Stromal-derived mesenchymal stem...