Dementia-linked amyloidosis is associated with brain protein deamidation as revealed by proteomic profiling of human brain tissues

Background: Aggregation of malformed proteins is a key feature of many neurodegenerative diseases, but the mechanisms that drive proteinopathy in the brain are poorly understood. We aimed to characterize aggregated proteins in human brain tissues affected by dementia. Results: To characterize amy...

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Bibliographic Details
Main Authors: Adav, Sunil S., Gallart-Palau, Xavier, Tan, Kok Hian, Lim, Sai Kiang, Tam, James Pingkwan, Sze, Siu Kwan
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10356/82857
http://hdl.handle.net/10220/40312
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Institution: Nanyang Technological University
Language: English

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