Electron microscopy and biochemical analysis of native telomeric chromatin

Human telomeres are G-rich sequence repeats of DNA that span the terminal ends of chromosomes with an average length of about 10,000 base pairs. Telomeric DNA acts as a platform for the recruitment of a six protein-complex called shelterin. The shelterin complex protects chromosome ends from fusion...

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Bibliographic Details
Main Author: Ahsan, Bilal
Other Authors: Sara Sandin
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2019
Subjects:
Online Access:https://hdl.handle.net/10356/85247
http://hdl.handle.net/10220/49204
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Institution: Nanyang Technological University
Language: English

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