Dearylation of arylphosphine oxides using a sodium hydride–iodide composite

A new protocol for the dearylation of arylphosphine oxides was developed using sodium hydride (NaH) in the presence of lithium iodide (LiI). The transient sodium phosphinite could be functionalized with a range of electrophiles in a one-pot fashion.

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Bibliographic Details
Main Authors: Tejo, Ciputra, Pang, Jia Hao, Ong, Derek Yiren, Oi, Miku, Uchiyama, Masanobu, Takita, Ryo, Chiba, Shunsuke
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10356/85913
http://hdl.handle.net/10220/48244
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Institution: Nanyang Technological University
Language: English
Description
Summary:A new protocol for the dearylation of arylphosphine oxides was developed using sodium hydride (NaH) in the presence of lithium iodide (LiI). The transient sodium phosphinite could be functionalized with a range of electrophiles in a one-pot fashion.