Systematic evaluation of CRISPR-Cas systems reveals design principles for genome editing in human cells

Systematic evaluation of CRISPR-Cas systems reveals design principles for genome editing in human cells

Background: While CRISPR-Cas systems hold tremendous potential for engineering the human genome, it is unclear how well each system performs against one another in both non-homologous end joining (NHEJ)-mediated and homology-directed repair (HDR)-mediated genome editing. Results: We systematically c...

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書目詳細資料
Main Authors:	Wang, Yuanming, Liu, Ivy Kaiwen, Sutrisnoh, Norfala-Aliah, Srinivasan, Harini, Zhang, Junyi, Li, Jia, Zhang, Fan, Lalith, Charles Richard John, Xing, Heyun, Shanmugam, Raghuvaran, Foo, Jia Nee, Yeo, Hwee Ting, Ooi, Kean Hean, Bleckwehl, Tore, Par, Rachel Yi Yun, Lee, Shi Mun, Ismail, Nur Nadiah, Sanwari, Nur Aidah, Lee, Vanessa Si Ting, Lew, Jan, Tan, Meng How
其他作者:	School of Chemical and Biomedical Engineering
格式:	Article
語言:	English
出版:	2018
主題:	CRISPR Genome Editing
在線閱讀:	https://hdl.handle.net/10356/87501 http://hdl.handle.net/10220/45417
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!

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