Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome
The long terminal repeat (LTR) of the proviral human immunodeficiency virus (HIV)-1 genome is integral to virus transcription and host cell infection. The guanine-rich U3 region within the LTR promoter, previously shown to form G-quadruplex structures, represents an attractive target to inhibit HIV...
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| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/88976 http://hdl.handle.net/10220/46042 |
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| Institution: | Nanyang Technological University |
| Language: | English |