Biomimicking fiber scaffold as an effective in vitro and in vivo microRNA screening platform for directing tissue regeneration

• Main Authors: Zhang, Na, Milbreta, Ulla, Chin, Jiah Shin, Pinese, Coline, Lin, Junquan, Shirahama, Hitomi, Jiang, Wei, Liu, Hang, Mi, Ruifa, Hoke, Ahmet, Wu, Wutian, Chew, Sing Yian
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2019
• Subjects: Electrospinning; DRNTU::Engineering::Chemical engineering; Contact Guidance
• Online Access: https://hdl.handle.net/10356/92947; http://hdl.handle.net/10220/48520
• Institution: Nanyang Technological University

MicroRNAs effectively modulate protein expression and cellular response. Unfortunately, the lack of robust nonviral delivery platforms has limited the therapeutic application of microRNAs. Additionally, there is a shortage of drug‐screening platforms that are directly translatable from in vitro to i...