Preferential interaction of the mRNA proofreading factor TFIIS zinc ribbon with rU·dA base pairs correlates with its function

The transcriptional factor TFIIS helps overcome elongation barriers and enhances proofreading by RNA polymerase II. These TFIIS functions may be modulated by the TFIIS zinc ribbon domain through interactions with nucleic acids in the elongation complex. Within this zinc ribbon domain, the dipeptide...

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Bibliographic Details
Main Authors: Sitikov, Albert S., Yoon, Ho Sup, Jeon, Choon Ju, Agarwal, Kan
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/10356/94267
http://hdl.handle.net/10220/7472
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Institution: Nanyang Technological University
Language: English

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