Enantioselective oxidative cross-dehydrogenative coupling of tertiary amines to aldehydes

• Main Authors: Zhang, Junmin, Tiwari, Bhoopendra, Xing, Chong, Chen, Xingkuan, Chi, Robin Yonggui
• 其他作者: School of Physical and Mathematical Sciences
• 格式: Article
• 語言: English
• 出版: 2012
• 主題: DRNTU::Science::Mathematics::Applied mathematics
• 在線閱讀: https://hdl.handle.net/10356/94637; http://hdl.handle.net/10220/8116
• 機構: Nanyang Technological University

An enantioselective and direct oxidative coupling of aldehydes to tertiary amines to give β-amino alcohols is described. Catalyzed by copper(II), the reaction proceeds to give a racemic mixture of products; however, by using a combination of copper(II) and a chiral amine catalyst, the reaction gives...