Enantioselective oxidative cross-dehydrogenative coupling of tertiary amines to aldehydes

• المؤلفون الرئيسيون: Zhang, Junmin, Tiwari, Bhoopendra, Xing, Chong, Chen, Xingkuan, Chi, Robin Yonggui
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2012
• الموضوعات: DRNTU::Science::Mathematics::Applied mathematics
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/94637; http://hdl.handle.net/10220/8116
• المؤسسة: Nanyang Technological University

An enantioselective and direct oxidative coupling of aldehydes to tertiary amines to give β-amino alcohols is described. Catalyzed by copper(II), the reaction proceeds to give a racemic mixture of products; however, by using a combination of copper(II) and a chiral amine catalyst, the reaction gives...