Exploring the mechanism of Zanamivir resistance in a neuraminidase mutant : a molecular dynamics study
It is critical to understand the molecular basis of the drug resistance of influenza viruses to efficiently treat this infectious disease. Recently, H1N1 strains of influenza A carrying a mutation of Q136K in neuraminidase were found. The new strain showed a strong Zanamivir neutralization effect. I...
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Main Authors: | Han, Nanyu, Liu, Xue-Wei, Mu, Yuguang |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2013
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/95313 http://hdl.handle.net/10220/9270 |
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Institution: | Nanyang Technological University |
Language: | English |
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