C–C bond formation via copper-catalyzed conjugate addition reactions to enones in water at room temperature
Conjugate addition reactions to enones can now be done in water at room temperature with in situ generated organocopper reagents. Mixing an enone, zinc powder, TMEDA, and an alkyl halide in a micellar environemnt containing catalytic amounts of Cu(I), Ag(I), and Au(III) leads to 1,4-adducts in good...
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Main Authors: | Isley, Nicholas A., Lipshutz, Bruce H., Huang, Shenlin, Leong, Wendy Wen Yi, Zhong, Guofu |
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Other Authors: | School of Physical and Mathematical Sciences |
Format: | Article |
Language: | English |
Published: |
2013
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Online Access: | https://hdl.handle.net/10356/95853 http://hdl.handle.net/10220/11287 |
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Institution: | Nanyang Technological University |
Language: | English |
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