Lack of Smad3 signaling leads to impaired skeletal muscle regeneration

Smad3 is a key intracellular signaling mediator for both transforming growth factor-β and myostatin, two major regulators of skeletal muscle growth. Previous published work has revealed pronounced muscle atrophy together with impaired satellite cell functionality in Smad3-null muscles. In the presen...

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Bibliographic Details
Main Authors: Sharma, Mridula, McFarlane, Craig, Wahli, Walter, Ge, Xiaojia, Vajjala, Anuradha, Kambadur, Ravi
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2013
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Online Access:https://hdl.handle.net/10356/98518
http://hdl.handle.net/10220/12445
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Institution: Nanyang Technological University
Language: English

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