Controlling fibrous capsule formation through long-term down-regulation of collagen type I (COL1A1) expression by nanofiber-mediated siRNA gene silencing
The foreign body reaction often interferes with the long-term functionality and performance of implanted biomedical devices through fibrous capsule formation. While many implant modification techniques have been adopted in attempts to control fibrous encapsulation, the outcomes remained sub-optimal....
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Main Authors: | Rujitanaroj, Pim-On, Jao, Brian, Yang, Junghoon, Wang, Feng, Anderson, James M., Wang, Jun, Chew, Sing Yian |
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其他作者: | School of Chemical and Biomedical Engineering |
格式: | Article |
語言: | English |
出版: |
2013
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在線閱讀: | https://hdl.handle.net/10356/99728 http://hdl.handle.net/10220/9960 |
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