First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway

First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway

10.1158/1078-0432.CCR-11-2470

Saved in:

Bibliographic Details
Main Authors:	Manu, K.A., Shanmugam, M.K., Ramachandran, L., Li, F., Fong, C.W., Kumar, A.P., Tan, P., Sethi, G.
Other Authors:	CANCER SCIENCE INSTITUTE OF SINGAPORE
Format:	Article
Published:	2014
Online Access:	http://scholarbank.nus.edu.sg/handle/10635/109345
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	National University of Singapore

Similar Items

γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: Potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent
by: Rajendran, P., et al.
Published: (2014)

Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products
by: Manu, K.A., et al.
Published: (2014)

Role of NF-κB in tumorigenesis
by: Shanmugam, M.K., et al.
Published: (2014)

γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model
by: Siveen, K.S., et al.
Published: (2014)

Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells
by: Kannaiyan, R., et al.
Published: (2014)

Inactivation of AKT/NF-κB signaling by eurycomalactone decreases human NSCLC cell viability and improves the chemosensitivity to cisplatin
by: Nahathai Dukaew, et al.
Published: (2020)

Inactivation of AKT/NF-κB signaling by eurycomalactone decreases human NSCLC cell viability and improves the chemosensitivity to cisplatin
by: Nahathai Dukaew, et al.
Published: (2020)

Celastrol attenuates the invasion and migration and augments the anticancer effects of bortezomib in a xenograft mouse model of multiple myeloma
by: Shanmugam, M.K, et al.
Published: (2020)

?-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model
by: Siveen K.S., et al.
Published: (2020)

Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-?B regulated gene products in multiple myeloma xenograft mouse model
by: Siveen, K.S, et al.
Published: (2020)

Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer
by: Ramachandran, L., et al.
Published: (2014)

Evidence for the involvement of the master transcription factor NF-κB in cancer initiation and progression
by: Puar, Y.R, et al.
Published: (2020)

Interleukin-8 associated with chemosensitivity and poor chemotherapeutic response to gastric cancer
by: Sirikan Limpakan, et al.
Published: (2020)

Reduced plasma APOA1 level is associated with Gastric Tumor Growth in MKN45 mouse xenograft model
by: Chong, P.-K., et al.
Published: (2014)

Targeting transcription factor NF-κB to overcome chemoresistance and radioresistance in cancer therapy
by: Li, F., et al.
Published: (2011)

Tocotrienol fortification in eggs
by: Kiyotaka Nakagawa, et al.
Published: (2018)

Tocotrienol fortification in eggs
by: Kiyotaka Nakagawa, et al.
Published: (2018)

Review : tocotrienols chemistry
by: Joharie Mohd Said
Published: (2010)

The correlation between vitamin D and levels of IFN-γ, NF-κB, thyroid antibodies in down syndrome: study in Indonesian children
by: Yuni Hisbiyah, -, et al.

The correlation between vitamin D and levels of IFN-γ, NF-κB, thyroid antibodies in down syndrome: study in Indonesian children
by: Yuni Hisbiyah, -, et al.

The correlation between vitamin D and levels of IFN-γ, NF-κB, thyroid antibodies in down syndrome: study in Indonesian children
by: Yuni Hisbiyah, -, et al.

The correlation between vitamin D and levels of IFN-γ, NF-κB, thyroid antibodies in down syndrome: study in Indonesian children
by: Yuni Hisbiyah, -, et al.
Published: (2023)

Fisetin, a bioactive flavonol, attenuates allergic airway inflammation through negative regulation of NF-κB
by: Goh, F.Y., et al.
Published: (2014)

Molecular integrative clustering of asian gastric cell lines revealed two distinct chemosensitivity clusters
by: Choong M.L., et al.
Published: (2019)

NF-κB activation: Is it really redox regulated?
by: Clement, M.-V.
Published: (2013)

Targeting nf-κb signaling for multiple myeloma
by: Wong, A.H.-H., et al.
Published: (2021)

Curcumin as chemosensitizer
by: Limtrakul P.
Published: (2014)

Curcumin as chemosensitizer
by: Pornngarm Limtrakul
Published: (2018)

Association of DNA repair and drug transporter in relation to chemosensitivity in primary culture of Thai gastric cancer patients
by: Pattama Wongsirisin, et al.
Published: (2018)

NF-κB signaling in neurite growth and neuronal survival
by: Yu, F., et al.
Published: (2014)

The role of ELKS isoforms in leptin and NF-κB signaling.
by: Woo, Yissue.
Published: (2012)

Molecular mechanisms of action of tocotrienols in cancer: Recent trends and advancements
by: Aggarwal, V., et al.
Published: (2021)

Potent Anti-Inflammatory Activity of Ursolic Acid, a Triterpenoid Antioxidant, Is Mediated through Suppression of NF-κB, AP-1 and NF-AT
by: Checker R., et al.
Published: (2018)

NMR structure of Carcinoscorpius rotundicauda thioredoxin-related protein 16 and its role in regulating transcription factor NF-κB activity
by: Giri, P.K., et al.
Published: (2014)

Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells
by: Chua, A.W.L., et al.
Published: (2014)

Novel 1,3,4-oxadiazole induces anticancer activity by targeting NF-κB in hepatocellular carcinoma cells
by: Mohan, C.D, et al.
Published: (2020)

The Role of Capecitabine in the Management of Colorectal Cancer
by: Ugroseno Yudho Bintoro, Siprianus
Published: (2013)

Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers
by: Li F., et al.
Published: (2020)

Thymoquinone Inhibits Tumor Growth and Induces Apoptosis in a Breast Cancer Xenograft Mouse Model: The Role of p38 MAPK and ROS
by: Woo, C.C., et al.
Published: (2014)

Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo
by: Nirvanappa A.C., et al.
Published: (2018)