Mouse transgenesis identifies conserved functional enhancers and cis-regulatory motif in the vertebrate LIM homeobox gene Lhx2 locus

• Main Authors: Lee A.P., Brenner S., Venkatesh B.
• Other Authors: MEDICINE
• Format: Article
• Published: 2019
• Subjects: LIM protein; transcription factor; DNA binding protein; homeodomain protein; LHX2 protein, human; Lhx2 protein, mouse; membrane protein; animal experiment; animal tissue; article; central nervous system; controlled study; Crb2 gene; embryo; enhancer region; gene control; gene expression profiling; gene function; gene locus; gene mutation; genetic conservation; genetic variability; human; human tissue; Lhx2 gene; mouse; neural tube; nonhuman; nucleotide sequence; prediction; protein motif; reporter gene; spinal ganglion; tissue specificity; transgenic mouse; transgenics; animal; animal embryo; chicken; genetics; in situ hybridization; metabolism; vertebrate; Mammalia; Mus musculus; Pisces; Takifugu; Vertebrata; Animals; Chickens; Conserved Sequence; DNA-Binding Proteins; Embryo, Mammalian; Enhancer Elements, Genetic; Homeodomain Proteins; Humans; In Situ Hybridization; Membrane Proteins; Mice; Mice, Transgenic; Transcription Factors; Vertebrates
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/162049
• Institution: National University of Singapore

10.1371/journal.pone.0020088