Cell Specific eQTL Analysis without Sorting Cells

• Main Authors: Westra H.-J., Arends D., Esko T., Peters M.J., Schurmann C., Schramm K., Kettunen J., Yaghootkar H., Fairfax B.P., Andiappan A.K., Li Y., Fu J., Karjalainen J., Platteel M., Visschedijk M., Weersma R.K., Kasela S., Milani L., Tserel L., Peterson P., Reinmaa E., Hofman A., Uitterlinden A.G., Rivadeneira F., Homuth G., Petersmann A., Lorbeer R., Prokisch H., Meitinger T., Herder C., Roden M., Grallert H., Ripatti S., Perola M., Wood A.R., Melzer D., Ferrucci L., Singleton A.B., Hernandez D.G., Knight J.C., Melchiotti R., Lee B., Poidinger M., Zolezzi F., Larbi A., Wang D.Y., van den Berg L.H., Veldink J.H., Rotzschke O., Makino S., Salomaa V., Strauch K., Völker U., van Meurs J.B.J., Metspalu A., Wijmenga C., Jansen R.C., Franke L.
• Other Authors: BIOLOGICAL SCIENCES
• Format: Article
• Published: Public Library of Science 2020
• Subjects: caspase recruitment domain protein 15; NOD2 protein, human; Article; cell selection; cell specificity; cohort analysis; controlled study; Crohn disease; downstream processing; gene expression profiling; genotype environment interaction; lymphocyte; neutrophil; NOD2 gene; quantitative trait locus mapping; single nucleotide polymorphism; cell line; cytology; gene expression regulation; genetics; genome-wide association study; human; meta analysis; metabolism; phenotype; principal component analysis; procedures; quantitative trait locus; reproducibility; Cell Line; Crohn Disease; Gene Expression Regulation; Genome-Wide Association Study; Humans; Lymphocytes; Neutrophils; Nod2 Signaling Adaptor Protein; Phenotype; Polymorphism, Single Nucleotide; Principal Component Analysis; Quantitative Trait Loci; Reproducibility of Results
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165392
• Institution: National University of Singapore

10.1371/journal.pgen.1005223