Nimotuzumab increases the anti-tumor effect of photodynamic therapy in an oral tumor model

• Main Authors: Bhuvaneswari, R, Ng, Q.F, Thong, P.S.P, Soo, K.-C
• Other Authors: PHYSICS
• Format: Article
• Published: Impact Journals LLC 2020
• Subjects: CD31 antigen; cetuximab; chlorin e6; epidermal growth factor receptor; Ki 67 antigen; nimotuzumab; photosensitizing agent; unclassified drug; EGFR protein, human; monoclonal antibody; phytochlorin; porphyrin; radiosensitizing agent; animal experiment; animal model; antiangiogenic activity; antineoplastic activity; antiproliferative activity; apoptosis; Article; cancer inhibition; cancer size; cell invasion; chemotaxis; concentration response; controlled study; down regulation; drug potentiation; drug safety; endothelium cell; extracellular matrix; HSC 3 cell line; human; human cell; immunohistochemistry; kidney function; light exposure; liver function; migration inhibition; mouth squamous cell carcinoma; nonhuman; oral cancer cell line; photodynamic therapy; SCC 25 cell line; therapy effect; treatment response; tumor xenograft; umbilical vein endothelial cell; animal; antagonists and inhibitors; Bagg albino mouse; biosynthesis; Carcinoma, Squamous Cell; cell proliferation; drug effects; drug screening; enzymology; Head and Neck Neoplasms; mouse; Mouth Neoplasms; multimodality cancer therapy; nude mouse; pathology; photochemotherapy; procedures; randomization; tumor cell line; Animals; Antibodies, Monoclonal, Humanized; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Drug Synergism; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Photochemotherapy; Porphyrins; Radiation-Sensitizing Agents; Random Allocation; Receptor, Epidermal Growth Factor; Xenograft Model Antitumor Assays
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175527
• Institution: National University of Singapore

10.18632/oncotarget.3622