Early spatiotemporal-specific changes in intermediate signals are predictive of cytotoxic sensitivity to TNF? and co-treatments

• Main Authors: Loo, L.-H, Bougen-Zhukov, N.M, Tan, W.-L.C
• Other Authors: DEPT OF PHARMACOLOGY
• Format: Article
• Published: 2020
• Subjects: antineoplastic agent; protein kinase inhibitor; transcriptome; tumor marker; tumor necrosis factor; biological model; cell survival; dose response; drug effect; drug resistance; gene expression regulation; genetics; human; lung tumor; metabolism; mutation; non small cell lung cancer; phosphorylation; protein transport; signal transduction; tumor cell line; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Models, Biological; Mutation; Phosphorylation; Protein Kinase Inhibitors; Protein Transport; Signal Transduction; Transcriptome; Tumor Necrosis Factor-alpha
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178690
• Institution: National University of Singapore

10.1038/srep43541